آسیب‌شناسی بافتی بیماری طاعون نشخوارکنندگان کوچک در بزها و گوسفندان منطقه سیستان

نوع مقاله: علمی پژوهشی

نویسندگان

1 دانش‌آموخته دکترای حرفه‌ای دامپزشکی، دانشکده دامپزشکی، دانشگاه زابل، زابل، ایران.

2 استادیار گروه پاتوبیولوژی، دانشکده دامپزشکی، دانشگاه زابل، زابل، ایران.

3 استادیار گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه زابل، زابل، ایران.

چکیده

طاعون نشخوارکنندگان کوچک (peste des petits ruminants; PPR) بیماری­ ویروسی واگیردار مهم گوسفند و بز می­باشد. با توجه به اهمیت PPR در سیستان، مضرات اقتصادی ناشی از تلفات و هزینه­های درمانی، مصرف بالای گوشت دام به شیوه ذبح سنتی و عدم نظارت کافی بر سلامت دام‌ها، مطالعه حاضر با هدف آسیب­شناسی بافتی بیماری مذکور در جمعیت گوسفند و بز منطقه سیستان صورت گرفت. از 30 رأس گوسفند و بز گله­های مشکوک به بیماری، نمونه­های بافتی از دهان، ریه، روده‌ها و غدد لنفاوی جمع‌آوری و پس از تهیه مقطع مورد مطالعه میکروسکوپی قرار گرفتند. تعداد 9 نمونه دارای آسیب­های بافتی بودند.داده­ها با نرم‌افزار SPSS و آزمون کاپا مورد تحلیل آماری قرار گرفت. میزان آلودگی در گوسفند و بز به­ترتیب 25/33 و 88/38 درصد بود که ارتباط آماری معنی­داری بین گونه دامی و آسیب­های بافتی همچون تجمع سلول‌های آماسی چندهسته‌ای و تشکیل سلولهای سینسیتیا مشاهده شد (05/0>p). همچنینمیزان عفونت در سنین زیر دو سال و بالای دو سال به ترتیب 18/35و 8/22 درصدبود و ارتباط آماری معنی­داری از نظر سن دام و شدت تجمع سلول­های آماسی تک هسته‌ای هم وجود داشت (05/0>p). میزان آلودگی در جنس نر و ماده هم به ترتیب 98/49و 5/12 درصدبود و ارتباط آماریمعنی­داری از نظر جنسیت دام و میزان بروز آسیب­هایی چون تجمع سلول­های آماسی چندهسته‌ای، تشکیل سلول­های سینسیتیا وگنجیدگی‌های درون سیتوپلاسمی نیز مشاهده شد (05/0>p). این مطالعه نشان داد که PPRدر منطقه سیستان در بزهای زیر دو سال با احتمال وقوع بیشتر و ضایعات پاتولوژیک شدیدتری همراه است.

کلیدواژه‌ها


عنوان مقاله [English]

Histopathology of peste des petits ruminants in goats and sheep of Sistan region

نویسندگان [English]

  • Yasaman Derakhshan 1
  • Seyedeh Aida Davari 2
  • Ali sarani 3
1 D.V.M Graduate, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran.
2 Assistant Professor, Department of Pathobiology, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran.
3 Assistant Professor, Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran.
چکیده [English]

Peste-des-petits ruminants, is an important viral contagious disease of sheep and goat. Considering the importance of PPR in Sistan region, its economic losses as a consequence of mortality and treatment expenses, the high consumption of animal meat in the traditional way of slaughter in this area and lack of adequate supervision on animal health, the present study was conducted with the aim of histopathological investigation of this disease in sheep and goats of Sistan region. Tissue specimens from mouth, lungs, intestines and lymph nodes of 30 cases from suspected flocks were collected and after tissue processing were microscopically examined. In microscopic investigation, lesions were observed in 9 specimens. The data were analyzed using SPSS software and Kappa test. The incidence of infection in sheep and goats was 33.25% and 38/88% respectively and significant association was observed between species and lesions such as multinucleated inflammatory cells accumulation and syncytial cells formation (p<0.05). Also, the infection rates in ruminants less than and more than two years old were 35.18% and 22.8%, respectively and significant statistical relationship was found between the age and the severity of mononuclear inflammatory cells accumulation (p<0.05). The contamination rates in males and females were 49.98% and 12.5%, respectively and significant statistical association was found between the sex and the incidence of lesions like multinucleated inflammatory cells accumulation, syncytial cells and intracytoplasmic inclusion bodies (p<0.05). The results of this study demonstrated that there is a higher incidence of PPR occurrence in Sistan region in goats less than two years old with much severe pathologic lesions.

کلیدواژه‌ها [English]

  • Histopathology
  • Peste-des-petits ruminants
  • Sheep
  • Goat
  • Sistan
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